Immunosuppressants and male reproduction

EZ Drobnis, AK Nangia, EZ Drobnis… - … on Male Fertility, 2017 - Springer
… are likely to impact negatively on male fertility endpoints, but … As we review in this chapter,
results in experimental species … negative effect of sulfasalazine on semen quality and fertility. …

Quercetin and rutin ameliorates sulphasalazine‐induced spermiotoxicity, alterations in reproductive hormones and steroidogenic enzyme imbalance in rats

SO Osawe, EO Farombi - Andrologia, 2018 - Wiley Online Library
… This adverse effect of SASP on male reproduction has been linked to the nontherapeutic SP
… Osawe of ICT Department, NABTEB, Benin City, are also appreciated for the English review

The Association of Medications and Supplements with Male Reproductive Health: A Systematic Review.

A Alhamam, LR Garabed, S Julian, R Flannigan - Fertility and Sterility, 2023 - Elsevier
… In 1979, Toth published a case series of 6 patients on sulfasalazine (SASP) for ulcerative …
While a complete review of neoplasms and male fertility is beyond the scope of our review, it is …

[PDF][PDF] possess an antifertility activity in male rats

LM Lewin - academia.edu
male fertility by the same mechanism as this compound and were less toxic might be ideal
… Since the recognition of the side effects of sulphasalazine on male fertility, it has been …

Adverse Effects of Drugs on Male Reproduction

M Aubuchon, EZ Drobnis - Bioenvironmental Issues Affecting Men's …, 2018 - Elsevier
… with inflammatory bowel disease (IBD), those taking sulfasalazine had decreased sperm
count, motility, and normal morphology, while negative pregnancy outcomes have been …

Paternal exposure to antirheumatic drugs—what physicians should know: review of the literature

MC Micu, M Ostensen, PM Villiger, R Micu… - Seminars in arthritis and …, 2018 - Elsevier
effect on male reproduction are sparse. Thus far no sign of CS induced harmful effects have
Salicylazosulfapyridine (sulfasalazine, SSZ) is a sulfonamide transformed in the colon into …

Male fertility as a marker for health

T Chen, F Belladelli, F Del Giudice… - Reproductive BioMedicine …, 2022 - Elsevier
… The purpose of this review is to present an integrated overview of the existing literature
regarding male fertility as a marker for health (as assessed by genetics, health, exposures and …

Sulfasalazine exposure during pregnancy and lactation: reproductive outcomes in male rat offspring

S Forcato, AB de Oliveira Aquino… - Reproduction …, 2023 - CSIRO Publishing
… Moreover, male fertility was not affected, since the testosterone levels and … impairments in
sperm parameters that could compromise fertility. This study investigated the consequences of …

Pregnancy and medications in inflammatory bowel disease

RH Cao, MC Grimm - Obstetric Medicine, 2021 - journals.sagepub.com
… Whilst the focus of this review are women, concerns about fertility are also shared by … to
impact male fertility. However, specific IBD therapies do have an effect: sulfasalazine causes well-…

The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis

J Yee, SM Kim, JM Han, N Lee, HY Yoon, HS Gwak - Scientific reports, 2020 - nature.com
… In this review, we rated one point in each item of comparability, if age and other known risk
factors (such as sulfasalazine dose) were matched or adjusted in the analysis. The minimum …